diff --git a/requirements/main.txt b/requirements/main.txt
index 5fac1105..5db7550a 100644
--- a/requirements/main.txt
+++ b/requirements/main.txt
@@ -6,7 +6,7 @@ cffi == 1.12.2
 img2pdf == 0.3.3
 pdfminer.six == 20181108
 pikepdf == 1.6.5
-Pillow >= 5.0.0, != 5.1.0 ; sys_platform == "darwin"
+Pillow >= 6.2.0
 pycparser == 2.19
 python-xmp-toolkit == 2.0.1
 reportlab == 3.5.13
diff --git a/setup.py b/setup.py
index e9d167f2..b7d2e2d7 100644
--- a/setup.py
+++ b/setup.py
@@ -98,9 +98,7 @@ setup(
         'img2pdf >= 0.3.0, < 0.4',  # pure Python, so track HEAD closely
         'pdfminer.six == 20181108',
         'pikepdf >= 1.6.5, < 2',
-        'Pillow >= 4.0.0, != 5.1.0 ; sys_platform == "darwin"',
-        # Pillow < 4 has BytesIO/TIFF bug w/img2pdf 0.2.3
-        # block 5.1.0, broken wheels
+        'Pillow >= 6.2.0',
         'reportlab >= 3.3.0',  # oldest released version with sane image handling
         'tqdm >= 4',
     ],